Characterizations of Biocompatible and Bioactive Hydroxyapatite Particles

Authors

  • M. N. Salimi School of Bioprocess Engineering, Universiti Malaysia Perlis (UniMAP), Jejawi, Perlis
  • A. Anuar School of Bioprocess Engineering, Universiti Malaysia Perlis (UniMAP), Jejawi, Perlis

Abstract


Mathematics is a beautiful subject with logic applications. However,
the most common gene vectors used are virus based (viral gene vectors).
These possess high immunological risk, so a non-viral gene vector maybe
preferable. Nanocrystalline hydroxyapatite, HAp [Ca10(PO4)6(OH)2]
is an example of a possible non-viral gene vector. This is due to its good
biocompatibility, bioactivity and proven results as a non-viral gene vector.
The HAp particles produced in this study was by the sol-gel method
and the processing conditions were varied in terms of the processing
temperatures (20oC, 30oC or 40oC) and the stirring rates (200 rpm, 400
rpm or 600 rpm). The particles formed from all of the processing conditions
were systematically characterized and compared to each other. The
characterizations performed were FTIR, for identifying functional groups,
XRD for phase composition, crystallinity and particle size estimation
(by applying Scherrer’s formula) and SEM for surface morphology.The
characterizations data obtained showed that the functional groups, phase
composition, crystallinity and surface morphology were similar for all of
the samples, the only difference being on the calculated particle size. It also
showed that, at a lower processing temperature and higher stirring rate,
smaller particle sizes were formed.

Downloads

Published

2013-06-30

How to Cite

Salimi, M. N., & Anuar, A. (2013). Characterizations of Biocompatible and Bioactive Hydroxyapatite Particles. Journal of Engineering and Technology (JET), 4(1), 39–50. Retrieved from https://jet.utem.edu.my/jet/article/view/171

Issue

Vol. 4 No. 1 (2013): JOURNAL OF ENGINEERING AND TECHNOLOGY

Section

Articles

License

Thank you for your interest in submitting your manuscript to the Journal of Engineering and Technology (JET).

JET publishes only original works. Manuscripts must not be previously published or under consideration by any other publications. Papers published in JET may not be published again in whole or in part without permission. Please review these guidelines for researching, writing, formatting and submitting your manuscript. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).

Those submitting manuscripts should be carefully checked to ensure that all works contributed to the manuscript are acknowledged. The list of authors should include all those who can legitimately claim authorship. Manuscript should only be submitted for consideration once consent is given by all contributing authors using Transfer of Copyright form.